This is a second comparison:
Notice the hands do not change into fists on CTA clip. Do I have to do it manually or does the plugin able to track the changes?

you have to use the characters with 3d hands. Try using the dummy 3d characters that come with the beta 

@Magical Kingdom
the character itself comes with a sprite hand, to apply delicate 3D hand motion, you will need to change to a bone hand.
You can refer to the tutorial post here:  https://forum.reallusion.com/FindPost464020.aspx , and fast-foward to 2:49 to see how to change sprite hand to bone hand.