It does not matter how good your render looks, if your animation falls short. If you just want to render snapshots, you really don't have to
worry about animation. You could work on the thing you think is most important to your project, rendering or animation. If you work on half and half in
both, you may not get the results you want. Getting the scene how you want, takes the longest amount of time. 
I know I have more trouble with animating than getting a scene to look how I want it too. I can create a lot of different poses when combining 2 or 3 
animation poses using Motion Puppet. You can combine a phone call animation with a running or walking animation using Motion Puppet.
I like Motion Puppet a lot, because of all the different combinations I can get with it.
Your projects are based on how you set up a scene to render and animating a scene. Whatever you think you can do the best, try that first. Good luck.

Depends on the budget, time, and required effort you want to put in your project. There will always be time spent on learning how to use a software and researching it's capability. Some are easier to learn more than others. But the quirks, you will only know when you are actually using/researching the product. To summarize, here's what I realized:

To Produce Animated Video/Films and Games

• Big budget, More time = Character Creator, iClone, Blender, Unreal Engine and/or Unity + Other external tools (i.e. Zbrush, Marvelous Designer, Substance Painter, Blender add-ons, etc.)
• Big budget, Less time = Character Creator, iClone, Unreal Engine and/or Unity + Other external tools (i.e. Zbrush, Marvelous Designer, Substance Painter, Blender add-ons, etc.)
• Low budget, Less time = Character Creator, Blender (for basic stuff), Unreal Engine and/or Unity + Other low cost external tools
• Low budget, More time = Blender, Unreal Engine and/or Unity + Other low cost external tools

Unreal has lots of incredible, and free assets.  Unfortunately, I've not found a good way of getting those assets to iClone, so I may start using CC4 and IC8 for character creation and animation editing/creation, then attempt to make my movies in UE5.  But to make the best use of UE5, there's lots more to learn than there is in iClone, specifically particles and special effects.  But since I'm strictly a hobbyist, I find learning it slightly daunting.

yes that is what im after. im looking to make animations and movies.  seems like Unreal Engine is the one to go then??

that is another question.  what is the recommended Computer for having ICLONE and other applications.  The recommendation that was said when buying ICLONE I have heard is not enough, especially if you going to house other 3D software in your pipeline.

when is Unreal Engine 6 coming out???

very interesting on your posts.  so you are saying everything can be done with iclone.  looking at it, it seems Iclone when it comes processing polygons like Omniverse,  i dont see it come close.  also since there is now there is 8.1 with its new features that allows you to animate your work in Unreal Engine is pretty neat.   didnt know Blender had a FARM like that.   it is interesting just that the learning curve will be a bit much seeing as i have to learn Iclone, Character Creator, and now Unreal Engine.

This is the major problem in my vison, when you get a better computer RTX 3090, 64GB ram, i9 (for the best results) UE will going to version 6 in short of period of time and them you need to upgrade your machine again and again

RAG DOLL COLLISION ANIMATIONS FOR ICLONE 8 & 7
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Ghost Origins

My latest Feature length film created with Iclone.

My Sci- Fi Graphic Novel on Amazon: https://a.co/d/9k3cwoY

My IMDB listing
Anabran Abdhul Quarnain - IMDb

I think you really need to know something about both of those so I'd suggest going with whichever one will solve the biggest problem for you. I've spent the last year getting to grips with iClone and Character Creator, and now I'm moving on to learning Unreal because virtual production is where all the film and game industry interest (and therefore paid work) is in my area. 

Jeff Kirkland | Director • Cinematographer • Storyteller
Hobart • Tasmania • www.one18films.com
SYSTEM: AMD Ryzen 5 5500 | 32gb RAM | RTX 3060 12gb | 1tb SSD System | 44tb HDD Storage

I think Blender and Unreal are about equal, really comes down to your preference. Reallusion does have better tooling for Unreal, but it’s not really a decision maker difference if you get good with Blender. I think Omniverse is the best and easiest workflow, but it’s below both Blender and Unreal until auto hair and cloth physics is added.

Other than that last caveat, they are all great options. I could choose any of them happily. The only thing that would have me lean one way is if I was interested in intense, hi end ray traced animations that were very slow to render per frame. In that case, it’s really easy to rig up a command line Blender render farm on something like runpod.io and blast out renders fast for cheap vs using Omniverse. Even then, you could do something similar with Omniverse, but it’s more cumbersome and slow to setup and manage. If you denoise, I’m also not aware of how you can do it properly with temporal denoise across a home grown render farm (which is easy with Blender)