What sort of issues are you having with your iClone 5 renders?
What render format are you using, mpg., avi., image sequence?
What is the output resolution, 1280 x 720, 1980 x 1080?
No matter which version of iClone you are using, the best results can always be obtained by outputting either PNG. Image Sequences, or Uncompressed AVI files. Image sequences do not contain any Audio, while the AVI files have the Audio embedded.
System: Win 10 Pro (1803), Asus X99-E WS, CPU i7-5930K -3,5 GHz, 32 GB DDR4 2666-16 RAM, NVidia GTX 1080 Ti GPU - 11 GB VRAM(Driver 417.35), Samsung 850 Pro 512 GB SSD, 6 TB HD storage.