I agree with Rampa. Also having all of that doesn't mean anything and it's a problem I ran into since iC3. This is a 64 bit program, but with limitations on how big your project file can be. I use lots of avatars, props, and backgrounds, and have run into problems where the project size was just too big and I had to split things up. I will come on here later to post how I found, and what I've found that caused problems including this week, and how I got around it. I haven't seen every demo and looked at very little postings of others, but most of them have  been with 1-4 avatars in the same scene the most. Most of my scenes have no less than active 15 avatars in it. I went from a 2 GB to a 8 GB video card, and it improved nothing, and gave me the same exact problem. Plus unless I read it wrong, four GB of that video card memory is a waste (R9-290X), unless you are using two 4K monitors.  
 

Home built; ASRock X570 Pro 4, AMD Ryzen 9-5950X CPU, AMD RADEON RX6900XT, 16GB video card, 131GB of RAM.

I would like to amend this a bit. 4GB in a video card is NOT a waste. This is for the NVidia GTX series, I don't know about AMD. I work with large projects and the VRAM does get used. I also disagree with the statement about the CPU. It does matter, as I found out from an earlier to a later generation i7. Anyway, given the budget of the OP, we're not looking to build a budget computer.

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Interesting... Would you mind sharing, please, some rough benchmarking data, say, between an i5 (or older Quad Core) v/s earlier i7  v/s Later i7?  Secondly did you see any marked difference in performance between different spec Nvidia GTX graphics cards & can you quantify it somewhat? Thanks!