Hi, 
So I understand the following.
1. Unreal Engine 5 and Space Mouse Plugin (not affiliated with 3dConnexion) works great. Caveat - you have to ensure the 3dConnexion's own drivers are not activated or it won't work correctly. Tested on 20+ environments in Unreal. 
2. Movements in Iclone using 3dConnexion (I have enterprise edition) works opposite of what I'd expect. Tilt left, things move right. Tilt right, left. Tilt forward, I go backwards. 

I'm hoping there is a solution to things working in reverse with this. I'm left with hunch that their support isn't great. Their website is set for German and they can't localize the content?...so hardware is great, but software and drivers seems suspect.
Anyone else using their mouse and setup?
Thx