I don't think this issue will be related to the NVDIA driver.

The deletion of an exe file is (usually) caused by viruses or trojans.
The second possibility is that a failure in that partition of your disk (low probability) may cause your exe file to be deleted.
The third possibility (moderate probability) is that there is a problem with your regedit settings due to a mess in your operating system.
Sudden computer shutdown can also cause some files to be lost. For example, a power outage.
Another possibility is;
You may have manually deleted the exe file from your computer without realizing it. People can do really weird things without realizing it
For example, if there is a child at home who has access to a computer, this is a very common situation.

The only way to fix this is to uninstall and reinstall the program.
I can also suggest you to scan your computer with 2 different virus programs.
Check if there is a problem with your system by doing sfc / scannow from CMD.
You can use system restore, this might help clear up recent messes.

If you are insecure and suspect that you have other lost exe files, I suggest a clean install for your operating system.

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https://www.youtube.com/yepkoo
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Before doing anything else. Right click on the shortcut icon and select "Properties", when the properties window opens click on "Open File Location" and this should launch Windows Explorer with the .exe file highlighted. If that doesn't work then your only option is to try and uninstall the software and reinstall it. Just replacing an .exe file with a copy won't work because there may be other files or registry entries missing or corrupt. To make sure that you can do a clean fresh install it would be best to clean the registry using CCleaner or similar, the free version should be enough forthe job - but use it at your own risk. I use it almost daily and have never had any issues, but if you don't feel confident then get a friend who knows his/her stuff to do it.

Gerry

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System: Win 10 Pro (21H2), Asus X99-E WS, CPU i7-5930K -3,5 GHz, 32 GB DDR4 2666-16 RAM, NVidia GTX 1080 Ti GPU - 11 GB VRAM(Driver Studio-536.99), Samsung 850 Pro 512 GB SSD, 6 TB HD storage.