It is important to "clone" the drive rather than just copy. Because it is your system drive it needs to be bootable, obviously. Once you've done that, it should work.
I have done it once and I googled for instructions. There are various tools that let you clone.
If it doesn't work for some reason, you would need to put your old drive back and uninstall your RL products.
Then put your new drive back in and install your RL products. Before you do that, it is probably best to delete the Reallusion folder under C:\Program Files, as this will be recreated when you install.
Content you don't need to reinstall. If it is on your C: drive it will already have been copied over.