When baking a texture, UV islands must have wider margins.
I have this hi-poly dress, with multiple materials and Physics was not applying correctly to adjoining parts, because weight gradient maps were spanned between different materials.
So I decimated it and baked the texture with instaLOD. Now I have 1 material and 1 UV, but the UV islands packed so close and even coming in contact with one another, so that I practically cannot apply a weight map to it.

This is 3200% zoom of the UV map



One rogue vertex is enough to mess entire soft cloth physics for the garment.
And this what most likely to happen here. I did not even try. Do not want to waste time.
Now I have to spread those islands in Blender and possibly tweak the texture. (and someone who cannot do it would be doomed).

I thought, I'd still try, but after I saw this, it became totally out the question...
Round is a button, which should stay put. And it's crossing with free flow part of the dress.





FT: https://www.reallusion.com/FeedBackTracker/Issue/Insta-LOD-Islands-packing-for-Baking-Texture-has-no-margin

I did managed to bake all materials, textures and UVs in 3DCoat. Lot easier than in Blender. Now I can safely apply weight map with single gradient.

Could you show that 3dcoat bake workflow.

I bought 3DCoat like 3-4 years ago, bet never really used it much (I like the developer's (Andrey) courtesy, which allowed me to upgrade to the latest version for free today).

As to workflow, I followed this guidelines:



The only thing is, you have to import all texture manually for all materials (after you imported the mesh).