CC is not a mesh editing app like Blender. So no, it is not possible to do it in CC.
But you should not care how eyes or anything else appear in Blender.
You use it only to customize a cloth and bring it back to CC. You then save the customized cloth in CC, apply back your original character and apply newly saved cloth to it.
Then fix cloth materials.
Or export amended cloth only from Blender, import that cloth to CC as an accessory and then Transfer Skin Weight.
Either way work just fine.