This is a brief tutorial on how to bring Mixamo's animations into iClone using Adobe Fuse. You can do this using the free auto-rigger on their website, but Adobe Fuse characters are set up better, so you don't have to clean up the imported animations afterward.
1) Create an Adobe account (free), and download Adobe Fuse.
2) In Adobe Fuse, piece together standard character (I chose the base male). You can save time by right-clicking on a piece, and selecting the matching components.
3) Upload the character using the 'Save to Mixamo' option on the upper right corner.
4) Once uploaded, you will be connected to the Mixamo website. The Mixamo algorithm will auto-rig the character. Select the 'Standard Skeleton', which should be default. You can also enabled Shape Blends, but I don't think that matters. You do want the Standard Skeleton, which gives you the most bones. Finish, and choose 'Animate'.
5) Find some animations (I choose the Melee Combat Pack, which contains a series of sword wielding animations). Save to Assets, Download, and unzip into a folder.
6) Using the iClone 3DXchange Pipleline, import the main FBX file (e.g. BaseMale.fbx, FuseModel.fbx, etc.). Go to the Character Options (You can hit 'N' to shortcut there), and convert to Non-Standard.
7) In the Presets, select MayaHuman-IK, then 'Activate' and keep the 00_Tpose option selected, and Convert.
8) Go to the Animations (hit 'M' to shortcut there). Import the remaining FBX files into your Play List, then 'Add All to Perform'. Then export to iClone. Make sure you export the animations, with your dialog setup like this:
9) The animations will now by available in iClone, in your Custom Animations section, under the name that you exported your model ('e.g. BaseMale, FuseMale, etc.).
10) Now you can load up just about any iClone Character, and apply any of the animations and they will perform beautifully.