Might sound obvious but were you connected to the internet when you were trying to look at the online manual? If you were and were still unable to access the help guide then it would seem your security software is blocking access.I would take a look at your security or firewall settings and change them to allow full access for CTA. Once you do this you should be able to launch to the Reallusion site okay.
For your reference you can also find the online help guide by clicking the link below. :)
http://www.reallusion.com/crazytalk/Animator/help/animator/pro/