Hi..Sorry to hear of your problems with CrazyTalk Animator.
It clearly seems like your firewall or security software is blocking access to the Reallusion server to activate/deactivate your computer. You will need to make sure that full access is allowed for the software to complete this process. An open, active internet connection is required.
You can check all replies from Support in your Reallusion Account. Sometimes emails get filtered as spam/junk so keep a check in your account should this have happened.
As soon as you are able to sort out the connection issue you should be able to resolve the problem.