When working in ZBrush, it's important to verify whether the model is truly positioned at the origin.
While the model may visually appear to be at the origin, ZBrush's viewing and navigation tools can sometimes create the illusion of its position.
To confirm the model's location, you can check the X, Y, and Z positions in the Tool > Geometry > Position panel.
If all three values are 0, then the geometric center of the model aligns with the origin.
However, if the model's center is indeed at the origin in ZBrush, but it doesn't retain this position when imported into CC4, please consider reaching out to us by filling out the customer service form.
We will be more than happy to assist you in resolving this issue.
https://www.reallusion.com/CustomerSupport/UserEx/QForm.html