Yes , that happens when you tick CC_Setup without "saving all" after LL transfer.
Looks like UE4 has something like "double files "in the cache that could not be saved.
No problem , skip the save (it is already saved) do an UE4 restart , UE4 deletes the cache and it is working fine again without loosing anything :-)

Hope you still have 2 kidneys   

Thanks Bassline303. You are the best. 

I dont know if it is wise but I might not lose my Kidney I might wait for Big Navi since UE4's Chaos destruction is not dependent on Cuda Cores. Big Navi = higher memory + cheaper