The Hub itself doesn't take up much space so there shouldn't be a problem leaving it on the default C: drive.
However, you can install software like iClone on a different drive if you wish. If you currently have it on the C: drive you will need to uninstall first, then install again using the Hub and it will ask where you want to install it (see below). Just choose a different drive for the program files and content files by clicking the Browse buttons.
Peter
Forum Administrator
www.reallusion.com